Searchable abstracts of presentations at key conferences in endocrinology

ea0053cd2.2 | Case Discussions: complex clinical cases 2.0 | OU2018

Poor responsiveness after bariatric surgery: clinical and eating behaviour characteristics

Perez-Pevida Belen , Aldhwayanand Madhawi , Gibson Rachel , Scholtz Samantha , Miras Alexander D , McGlone Emma , Kamocka Anna , Khan Omar , Greener Veronica , McGowan Barbara , Rubino Francesco , Bloom Steve , Tan Tricia

Background: Bariatric surgery has been proven to produce substantial weight loss and amelioration of metabolic syndrome-associated co-morbidities. However, at five-year follow-up, only 20–40% of patients maintain diabetes remission and 40% of patients return to their baseline weight. The limiting factor in treating refractory diabetes following obesity surgery is the lack of knowledge about its aetiology.Aims: Evaluate the eating pattern and clinica...

ea0070aep374 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Liraglutide downregulates the expression of miRNA-424 in patients with obesity

Dimitriadis Georgios K , Dimitri Federica , Bate Danielle , Leca Bianca , Davasgaium Allan , Tripathi Gyanendra , Miras Alexander D , Rubino Francesco , Christian Mark , Randeva Harpal S

Aims: Liraglutide 3 mg once daily is an approved, prescription injectable Glucagon Like Peptide-1 receptor agonist that, when used with a low-calorie diet and increased physical activity, can reduce excess weight in patients with obesity. MiRNAs are small non-coding single stranded RNAs that regulate gene expression post-transcriptionally by inhibiting their mRNA target translation into proteins. MiRNAs can be secreted in the blood stream and affect the molecular pathways...